To calculate the result of the given expression, we simply add and subtract the numbers in the order they appear:
\[2 + 2 - 4 + 500 - 100 + 1 - 9 + 0\]
\[= (2 + 2 - 4) + 500 - 100 + 1 - 9 + 0\]
\[= (4 - 4) + 500 - 100 + 1 - 9 + 0\]
\[= 0 + 500 - 100 + 1 - 9 + 0\]
\[= 500 - 100 + 1 - 9 + 0\]
\[= (500 - 100) + 1 - 9 + 0\]
\[= 400 + 1 - 9 + 0\]
\[= (400 + 1) - 9 + 0\]
\[= 401 - 9 + 0\]
\[= 392\]
So, the result of the expression is \(392\).
